In this paper we investigate methods for testing the existence of a cointegration relationship among the components of a nonstationary fractionally integrated (NFI) vector time series. Our framework generalizes previous studies restricted to unit root integrated processes and permits simultaneous analysis of spurious and cointegrated NFI vectors. We propose a modified ‐statistic, based on a particular studentization, which converges weakly under both hypotheses, despite the fact that OLS estimates are only consistent under cointegration. This statistic leads to a Wald‐type test of cointegration when combined with a narrow band GLS‐type estimate. Our semiparametric methodology allows consistent testing of the spurious regression hypothesis against the alternative of fractional cointegration without prior knowledge on the memory of the original series, their short run properties, the cointegrating vector, or the degree of cointegration. This semiparametric aspect of the modelization does not lead to an asymptotic loss of power, permitting the Wald statistic to diverge faster under the alternative of cointegration than when testing for a hypothesized cointegration vector. In our simulations we show that the method has comparable power to customary procedures under the unit root cointegration setup, and maintains good properties in a general framework where other methods may fail. We illustrate our method testing the cointegration hypothesis of nominal GNP and simple‐sum (1, 2, 3) monetary aggregates.